Restless Sleep As You Age? Get Checked For Parkinsons..

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Random Points

Posted: May 6, 2013 in Random
Tags: ,
  1. Potency of steroids in topical application = clobetasol > mometasone > prednisone > methyl prednisone..
  2. Beta agonist-releases insulin; alfa agonist-blocks insulin release.
  3. ORCHITIS without EPIDYDYMITIS is seen in SYPHILLS.
  4. EPIDYDYMITIS without ORCHITIS is seen in GONORRHEA.
  5. HELMANS TRIAD in childhood is a good predictor of future voilent nature of child. It consists bed wetting+ fire setting +cruelty to animals.
  6. Calcium antagonizes the membrane actions of potassium and should be    administered for K >7 or any ECG changes
  7. Contraindicated in pregnancy: MCAT: Metronidazole, Chloramphenicol, Aminoglycoside, Tetracycline
  8. Infants fed with goat’s milk should be supplemented with folic acid.
  9. Macrocytic anemia of Diamond-Blackfan syndrome is with no
    hypersegmentation of the nucleus in neutrophils. Rx: corticosteroids.
  10. Early deceleration: fetal head compression.
    Late deceleration: uteroplacental insufficiency.
    Variable deceleration: cord compression.
  11. Digoxin is only used to treat atrial arrhythmias
  12. Pseudotumor cerebri causes a communicating hydrocephalus;
    therefore, an LP is considered safe.
  13. A PCWP < 18 mmHg suggests ARDS while a value > 18 mmHg
    suggests cardiogenic pulmonary edema
  14. The most common site for a lacunar infarct is the posterior internal
    capsule, producing a pure motor stroke
  15. 4 “T’s” of anterior mediastinum tumor:
    Thymoma,
    Thyoid neoplasm,
    Teratoma,
    Terrible lymphoma
  16. Renal vein thrombosis is most common with membranous
    glomerulonephritis.
  17. Cortex
    (positive selection) Thymic cortex. T cells expressing TCRs capable of binding surface self MHC molecules survive.
    Medulla
    (negative selection). T cells expressing TCRs with high affinity for self antigens undergo apoptosis.

MEDICOTIMES - PGMEE

Parkinsons plus syndromes have features of parkinsonism but they differ from parkinsons disease in having some additional features and they r unresponsive to treatments directed against parkinsons disease.

NOW LETS SEE HOW THEY COME TO NOTICE :

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EXAMPLES of PARKINSONS PLUS SYNDROMES  r ;

1] Multiple system atrophy

2] Progressive supranuclear palsy

3] Parkinsonism-dementia-amyotrophic lateral sclerosis comple

4] Corticobasal ganglionic degeneration

5] Diffuse lewy body disease

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PROGRESSIVE SUPRANUCLEAR PALSY

It is a tauopathy due to deposition of tau doublet 64 ,69.

CLINICAL FINDINGS:

1. Tremor is rare.

2. Supra nuclear vertical gaze palsy : supra nuclear nature of palsy can be checked by presence of vestibulo-ocular reflex which can be clinically assesed by vertical dolls eye maneuvers . There will be slowing of verical saccades.

3. presence of  square wave jerks ( Square-Wave Jerks (SWJ) are inappropriate saccades that take the eye off the target, followed by a nearly normal…

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MEDICOTIMES - PGMEE

NOTE ;This tric may take some time to remember but i promise it will take lesser time than plane memorisation and it will directly be stored in your NEOCORTEX bypassing ur HIPPOCAMPUS ; [Q HIPPOCAMPUS is site were shortterm memory is stored , processed and converted into long term memory which is then stored in neocortex].

CAUTION : LANGUAGE COMPATIBILITY = HINDI REQUIRED

ADVICE: THOSE WHO DONT LIKE LEARNING TRICKS SCROLL DOWN TO LOWEST FIGURE

Story;

SITA and GITA Stetho( ALA) lekar ghar se bahar nikle . Dhup me DEHYDRATE hokar PARESHAN ho gaye aur HOSPITAL pohonche .HOSPITAL me URINE output ko 3 litre pe CONTROL karke unko ghar wapas bhej diya gaya.Ghar me wo ab bohot PAANI   PEETE(drinks water) HAIN. HOSPITAL me unko ACP Rathod bhi mila who HAD VARIGATE & ERYTHEMATOUS face.

NOW SEE THE DIAGRAM/FLOW CHART BELOW

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STEP 1: SITA = SUCCINYL…

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MCQ ON PORPHYRIA

Posted: May 5, 2013 in Uncategorized

MEDICOTIMES - PGMEE

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ANS = C (SEE FIGURE BELOW)

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ANS =B (SEE FIGURE BELOW)

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ANS = D & E ( SEE FIGURE BELOW)

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ANS =E

In general enzyme inducers ppt porphyria so phenobarb , phenytoin , rifampicin will ppt porphyria.( SEE FIGURE BELOW)

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ans = E ( SEE FIGURE BELOW)

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ANS =D (SEE FIGURE OF Q2)

REFERENCE : HARRISONS 17ED PAGE 2434

HARRISON MANUAL OF INTERNAL MEDICINE 18 ED PG 1182

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MEDICOTIMES - PGMEE

FORENSIC BALLISTICS : Deals with investigation of firearms, ammunition and problem arising from their use.

TERMINAL BALLISTICS : STUDY OF BEHAVIOUR OF PROJECTILE WHEN IT HITS THE TARGET

FIGURE BELOW WILL SHOW U TYPES OF FIREARM:

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NOW KNOW WHAT IS BASIC DIFFERENCE B/W RIFFLED VS SHOTGUN

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NOW KNOW WHAT TYPE OF PROJECTILE IS USED IN FIREARMS

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FIGURE GIVEN BELOW WILL SHOW U THE DIFFERENT TYPES OF GUNPOWDER USED IN PROJECTILES:

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SOME IMPORTANT POINTS :

1.  In smooth bore  weapons range of fire can roughly be calculated by formula RANGE( IN METRE ) = D( IN cm) / 3   [ here D = maxm distance between outermost individual pellet]

eg if wounds inflicted by pellets is 20 cm apart then range of fire is about 7metre so we may conclude that this is not likely to be suicidal.

2] RICOCHET BULLET : strikes an intervening object first and then rebounds/ ricochets…

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FORENSIC BALLISTICS

MEDICOTIMES - PGMEE

NOTE : go through PART 1 OF THIS TOPIC FIRST, FOR BETTER UNDERSTANDING BY CLICKING ON LINK PROVIDED BELOW

http://pguploads.com/2013/04/21/forensic-ballistics-part-1-firearms-and-ammunitions/

Q1] IN A FIREARM INJURY THERE IS BURNING , BLAKENING , TATTOING AROUND THE WOUND, ALONG WITH CHERRY RED COLOUR OF SURROUNDING TISSUE AND IS CRUCIATE IN SHAPE , THE INJURY IS …..[AI 2005]

[A] CLOSE SHOT ENTRY

[B] CLOSE CONTACT EXIT

[C] CONTACT SHOT ENTRY

[D] DISTANT SHOT ENTRY

ANS = [A] CLOSE SHOT ENTRY

Presence of burning, blackening, tattoing signifies it to be close shot entry.

Cherry red colour at entrance wound is due to carbon monoxide that is formed due to flame that is produced from burning of gun powder at the entrance wound. Bcoz flame is found at short range the cherry red colour is seen contact > and close range shots only.

Cruciate shaped wound is seen when wound of entry is over a…

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